Doug DeBlasi's Bio:
Doug S. De Blasi is Business Development Manager for MMP, Inc. International
Development and Manufacturing in South Plainfield, New Jersey,a sourcing firm for
specialty cosmetic ingredients. Doug’s career began in applied organic polymer
research for both Sun Chemical Corporation and BASF Corporation. Doug made a
mid-career switch into sales and marketing in the early 90s when he created a new
division for Shamrock Technologies, Inc. and developed a patented line of fine
micronized polymers for color cosmetics and enhanced sunscreen formulations.
Since that early start Doug has developed Strategic Technical Marketing Programs
for four specialty ingredient firms.
Doug joined MMP, Inc. in 2010 where he specializes in skin care youth building and
advanced systems for emulsion stability. Doug holds a M.S. degree in organic
polymer chemistry and a M.B.A. in finance from Rutgers, The State University of New
Jersey.
Abstract for "An Innovative Model for Testing Natural Actives
and Delivering Their Topical Applications"
The popularity of natural ingredients for youthful skin care building has led to new
biological testing methods for plant derived extracts that measure skin care efficacy.
These methods benefit from an ample harvest of human skin tissue derived from the
parallel popularity of cosmetic surgeries. Additionally, since many extracts are
purified, knowledge of their unique solubilities is required to efficiently develop
aesthetically desirable skin care experiences. Pueraria Lobata Root Extract
(Puerarin) and Eucommia Ulmoides Leaf Extract (Chlorogenic Acids), two effective
purified natural extracts, will be presented along with their ex vivo results on human
skin explants,
Specific biological indicators of intrinsic dermal skin aging exist for the glycation
process and they provide evidence for damaging effects on skin proteins of the
extracellular matrix. A reference molecule, aminoguanidine HCl, will be introduced to
mitigate glycation along with the two selected plant extracts. The extracts are well
known in Asian traditional medicine for their beneficial effects in diabetes patients
where practitioners claim reduced blood glucose levels. This knowledge will be
applied to measure the reduced rate of glycation in human skin explants after topical
application. Finally, recommendations will be offered to efficiently introduce these
extracts into a stable delivery system suitable for topically applied, elegant skin care
products.
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